FDA label ladder

Semaglutide Wegovy label ladder to 2.4 mg: published ladder and modeled levels

Updated by the GLP Ladder Editorial Team. Editorial policy.

Short answer

Semaglutide Wegovy label ladder to 2.4 mg: 0.25/0.5/1/1.7/2.4 mg weekly, 4 weeks per step (Novo Nordisk, Jun 18, 2026). The final 2.4 mg step begins in week 17. With t½ 7 days and R = 2, the modeled amount peaks at 4.28 mg-eq. As published, not a recommendation; as of Oct 19, 2026.

Weeks per step
4 5 steps
Final step
2.4 mg from week 17
Modeled peak
4.28 mg-eq
Accumulation R
2 t½ 7 d
Semaglutide Wegovy label ladder to 2.4 mg: steps and modeled amountWeekly doses 0.25 mg, 0.5 mg, 1 mg, 1.7 mg, 2.4 mg; modeled amount peaks at 4.28 mg-equivalents.stable window01.252.53.755mg-eq048121620242832weeks from start0.25 mg0.5 mg1 mg1.7 mg2.4 mg
  • Weekly dose (published steps)
  • Modeled amount (mg-eq)
  • Stable window
Steps start on a Monday (Jan 5, 2026) for illustration. Curve: modeled relative amount, not plasma concentration. Open in the Semaglutide plotter to change dates or doses.
Wegovy label ladder to 2.4 mg: weeks, weekly dose and dates from a Jan 5, 2026 start (Novo Nordisk, Jun 18, 2026)
WeeksWeekly doseFirst week starts
1–4 0.25 mg Jan 5, 2026
5–8 0.5 mg Feb 2, 2026
9–12 1 mg Mar 2, 2026
13–16 1.7 mg Mar 30, 2026
17 onward 2.4 mg Apr 27, 2026

Weekly modeled amounts

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32 weeks. Highlighted rows start a new dose step. Model details: model card.

Semaglutide Wegovy label ladder to 2.4 mg: weekly peak, trough and average (mg-equivalents)
WeekStartsDose mgPeakTroughAverage
1Jan 5, 20260.250.21500.165
2Jan 12, 20260.250.330.1310.263
3Jan 19, 20260.250.3870.1970.312
4Jan 26, 20260.250.4160.2290.336
5Feb 2, 20260.50.6450.2460.513
6Feb 9, 20260.50.7680.3850.617
7Feb 16, 20260.50.8290.4550.669
8Feb 23, 20260.50.860.4890.695
9Mar 2, 202611.3030.5071.038
10Mar 9, 202611.5420.7771.24
11Mar 16, 202611.6620.9131.342
12Mar 23, 202611.7220.9811.392
13Mar 30, 20261.72.351.0141.879
14Apr 6, 20261.72.6891.3982.166
15Apr 13, 20261.72.8591.592.309
16Apr 20, 20261.72.9451.6862.381
17Apr 27, 20262.43.5841.7342.878
18May 4, 20262.43.932.1253.17
19May 11, 20262.44.1042.323.316
20May 18, 20262.44.1912.4183.389
21May 25, 20262.44.2352.4673.426
22Jun 1, 20262.44.2562.4913.444
23Jun 8, 20262.44.2672.5043.453
24Jun 15, 20262.44.2732.513.458
25Jun 22, 20262.44.2752.5133.46
26Jun 29, 20262.44.2772.5143.461
27Jul 6, 20262.44.2772.5153.462
28Jul 13, 20262.44.2782.5153.462
29Jul 20, 2026—2.61.3051.879
30Jul 27, 2026—1.30.6530.94
31Aug 3, 2026—0.650.3260.47
32Aug 10, 2026—0.3250.1630.235

Sources

  1. WEGOVY (semaglutide) injection, for subcutaneous use; WEGOVY (semaglutide) tablets, for oral use - Full Prescribing Information (SPL, Revised 6/2026). Novo Nordisk / National Library of Medicine DailyMed, Jun 18, 2026. Accessed Oct 19, 2026.

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